Vitamin D/dietary calcium deficiency rickets and pseudo-vitamin D deficiency rickets

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Hereditary Pseudo-Deficiency Rickets or Vitamin D-Dependency Type I

Following the description in 1937 by Albright, Butler, and Bloomberg (1) of "rickets resistant to vitamin D," a number of observations were published, particularly by Van Crefeld and Arons (2), Fraser and Salter (3), and by Royer (4) which indicated that there was a variant of resistant rickets which differed from classical hereditary hypophosphatemic vitamin D-resistant rickets by its clinical...

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Resurrection of vitamin D deficiency and rickets.

The epidemic scourge of rickets in the 19th century was caused by vitamin D deficiency due to inadequate sun exposure and resulted in growth retardation, muscle weakness, skeletal deformities, hypocalcemia, tetany, and seizures. The encouragement of sensible sun exposure and the fortification of milk with vitamin D resulted in almost complete eradication of the disease. Vitamin D (where D repre...

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Vitamin D Deficiency including Osteomalacia and Rickets

Adequate vitamin D3 by synthesis in the skin and from dietary and supplemental sources is essential for bone health throughout life. [1] Rickets in children and osteomalacia in adults are the classic but extreme manifestations of severe vitamin D deficiency. Links have also been shown between poor vitamin D status and breast cancer, bowel cancer, prostate cancer, lung cancer, metabolic syndrome...

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Vitamin-D deficiency rickets in Jamaican children.

Vitamin-D deficiency is not as rare in Jamaica as previously believed. 9 children with vitamin-D deficiency rickets have been seen at the University Hospital of the West Indies during the past 5 years. All were over 3 years of age at time of presentation. Both dietary deficiency of vitamin D and lack of exposure to sunlight seem to be important causes. Children living in rural Jamaica seem to b...

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ژورنال

عنوان ژورنال: BoneKEy Reports

سال: 2014

ISSN: 2047-6396

DOI: 10.1038/bonekey.2014.19